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How Fat Loss Works: Understanding the Science of Burning Body Fat

Mar 26, 2025

Written By

John Schaefer

Reviewed By

Paul Winsper, Chief Science and Performance Officer, AlterMe

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How Fat Loss Works: Understanding the Science of Burning Body Fat

Fat loss is often oversimplified as “eat less, move more.” While that statement isn’t entirely wrong, it leaves out critical details about how your body burns fat, where your energy comes from, and what truly drives sustainable progress. If you’ve ever wondered why some diets work and others fail, or why fat loss can feel so slow, understanding the science behind how fat loss works can make all the difference.

Let’s break it down so you can take a smarter, more effective approach to your goals.

The Basics of Fat Loss: Calories In vs. Calories Out

At the core of fat loss is energy balance—the relationship between the calories you consume and the calories your body burns. If you consistently consume more calories than you burn, the excess energy is stored as fat. On the flip side, if you burn more calories than you consume, your body taps into stored fat for energy, leading to fat loss.

This is known as a caloric deficit and is the single most important factor in reducing body fat. No diet, exercise plan, or supplement will override the need for a calorie deficit.

But while the concept of “eat less, move more” is technically true, it doesn’t mean fat loss is just about extreme restriction. The way your body burns calories—and whether it burns carbs or fat—depends on how you fuel it and how you move.

How Your Body Uses Energy: The Fueling System

Your body primarily relies on three macronutrients for energy: carbohydrates, fats, and proteins. Each plays a role in your metabolism, but they don’t all get used the same way.

  • Carbohydrates – The body’s preferred and most immediate energy source. When you eat carbs, they’re broken down into glucose and either used for energy or stored as glycogen in your muscles and liver.
  • Fat – Your long-term energy reserve. When your body isn’t getting enough immediate energy from food, it turns to stored fat for fuel.
  • Protein – Primarily used for muscle repair and bodily functions, protein is not a major energy source unless your body is in starvation mode.

Think of your body like a wood-burning stove:

  • Carbs are like kindling—they burn quickly and provide immediate energy.
  • Fat is like a slow-burning log—it provides steady, long-lasting energy, but only once the kindling burns out.

Your body burns carbs first, then shifts to burning fat when glycogen stores are low. This is why fasting, low-carb diets, and endurance exercise can increase fat burning—they deplete glycogen faster, forcing your body to rely on fat for fuel.

The Science of Fat Burning: Lipolysis & Fat Oxidation

Fat loss happens in two key steps:

  1. Lipolysis – Your body breaks down fat stores into fatty acids.
  2. Fat Oxidation – These fatty acids are transported to the muscles and burned for energy.

However, fat isn’t burned unless your body needs to use it. If you’re eating more calories than you burn, your body has no reason to dip into fat stores. This is why exercise and nutrition work together—physical activity increases calorie burn, while a caloric deficit forces your body to rely on fat for fuel.

One often overlooked factor is hydration. Your body requires water to break down fat effectively. Without proper hydration, fat metabolism becomes less efficient, making it harder to lose weight.

Why Strength Training is Crucial for Fat Loss

Many people focus only on cardio for fat loss, but strength training is just as—if not more—important.

Muscle is metabolically active, meaning it burns calories even at rest. The more muscle you have, the higher your resting metabolic rate (RMR), meaning your body naturally burns more calories throughout the day—even while you sleep.

Here’s why strength training supports fat loss:

  • Preserves muscle while in a calorie deficit, preventing metabolic slowdown
  • Increases post-workout calorie burn (EPOC effect)
  • Builds lean mass, which raises your daily energy expenditure over time

The Role of Cardio in Fat Loss

While strength training is foundational, cardio plays a complementary role in achieving a calorie deficit and supporting cardiovascular health.

  • Low-Intensity Steady-State Cardio (LISS) – Walking, biking, or light jogging at a steady pace primarily burns fat and helps with recovery.
  • High-Intensity Interval Training (HIIT) – Short bursts of intense effort followed by rest or low-intensity recovery. HIIT increases total calorie burn and enhances post-exercise fat oxidation.

One of the most effective approaches is Zone 2 training—moderate-intensity cardio that keeps your heart rate at 60–70% of its maximum. This targets fat metabolism, improves endurance, and supports overall metabolic flexibility.

Common Myths About Fat Loss

There’s a lot of misinformation out there. Let’s clear up a few persistent fat loss myths:

  • “Eating fat makes you fat.” Not true. Excess calories, not dietary fat, cause fat gain. Healthy fats (like avocado, nuts, and olive oil) are essential for hormone function and satiety.
  • “You need to eat six small meals a day to boost metabolism.” Meal frequency doesn’t matter as much as total calorie intake. Some people do well with multiple small meals, while others prefer larger meals in a shorter window (like intermittent fasting).
  • “Low-carb diets are the only way to lose fat.” While low-carb diets can help some people manage appetite and blood sugar, fat loss still comes down to a calorie deficit. You can lose fat while eating carbs, as long as you stay in that deficit.

How to Make Fat Loss Sustainable

Lasting fat loss doesn’t come from aggressive diets or all-or-nothing plans. It comes from small, consistent actions that fit your life:

  1. Strength train 2–4 times per week to build or maintain muscle mass
  2. Stay in a moderate calorie deficit—not too steep, not too small
  3. Eat enough protein to stay full and protect muscle (aim for 0.6–1g per lb of goal body weight)
  4. Increase daily movement—walking, steps, and light activity matter
  5. Prioritize hydration for fat metabolism and digestion

Applying the Principles of Fat Loss

Fat loss isn’t about shortcuts—it’s about understanding your body and making consistent, informed choices. When you create a small calorie deficit, move intentionally, prioritize protein, and build strength, your body will respond.

Progress might feel slow at times, but that’s how real, sustainable fat loss works. It’s not about perfection. It’s about stacking small wins daily and staying committed to your long-term goal.

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